金澤宏樹

カナザワヒロキ (Hiroki Kanazawa)

基本情報

立体構造解析を主な手法として機能性RNAの研究に取り組んでいます。今後はtRNA医薬品やmRNA医薬品の設計開発、Structure-based RNA design、その工場スケールでの大量生産と流通などの研究に携わりたいと考えています。

Methods to Analyze Post-transcriptional Modifications Applied to Stable RNAs in Staphylococcus aureus

Roberto Bahena-Ceron, Jose Jaramillo-Ponce, Hiroki Kanazawa, Laura Antoine, Philippe Wolff, Virginie Marchand, Bruno P. Klaholz, Yuri Motorin, Pascale Romby, Stefano Marzi

RNA Technologies 2023年
Inside Back Cover: Crystal structure of a NIR‐Emitting DNA‐Stabilized Ag16 Nanocluster (Angew. Chem. Int. Ed. 48/2019)

Cecilia Cerretani, Hiroki Kanazawa, Tom Vosch, Jiro Kondo

Angewandte Chemie International Edition 58(48) 17481-17481 2019年11月25日
Innenrücktitelbild: Crystal structure of a NIR‐Emitting DNA‐Stabilized Ag16 Nanocluster (Angew. Chem. 48/2019)

Cecilia Cerretani, Hiroki Kanazawa, Tom Vosch, Jiro Kondo

Angewandte Chemie 131(48) 17643-17643 2019年11月25日
Crystal structure of a NIR‐Emitting DNA‐Stabilized Ag16 Nanocluster

Cecilia Cerretani, Hiroki Kanazawa, Tom Vosch, Jiro Kondo

Angewandte Chemie 131(48) 17313-17317 2019年11月25日
Crystal structure of a NIR‐Emitting DNA‐Stabilized Ag16 Nanocluster

Cecilia Cerretani, Hiroki Kanazawa, Tom Vosch, Jiro Kondo

Angewandte Chemie International Edition 58(48) 17153-17157 2019年11月25日

Structure-based design of a eukaryote-selective aminoglycoside

Hiroki Kanazawa, Oscar M. Saavedra, Juan Pablo Mianti, Simon A. Young, Luis Izquierdo, Terry K. Smith, Stephen Hanessian, Jiro Kondo

The 45th International Symposium on Nucleic Acids Chemistry 2018 The 2nd Annual Meeting of Japan Society of Nucleic Acids Chemistry 2018年11月
Crystal structure of the human ribosomal decoding A site in complex with G418 possessing readthrough activity

Hiroki Kanazawa, Nao Tsurumi, Jiro Kondo

The 44th International Symposium on Nucleic Acids Chemistry 2017 The 1st Annual Meeting of Japan Society of Nucleic Acids Chemistry 2017年
Interactions between the bacterial ribosomal RNA and fluorinated aminoglycosides

Hiroki Kanazawa, Juan Pablo Maianti, Stephen Hanessian, Jiro Kondo

The 21st Annual Meeting of the RNA society 2016年
Structural insights into the catalytic reaction trigger and inhibition of D-3-hydroxybutyrate dehydrogenase

Hiroki Kanazawa, Md. Mominul Hoque, Masaru Tsunoda, Kaoru Suzuki, Tamotsu Yamamoto, Gota Kawai, Jiro Kondo, Akio Takénaka

30th European Crystallographic Meeting 2016年
Crystal structures of the bacterial ribosomal RNA in complex with fluorinated aminoglycosides

Hiroki Kanazawa, Juan Pablo Maianti, Stephen Hanessian, Jiro Kondo

The 43rd International Symposium on Nucleic Acids Chemistry 2016年