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Researcher List >> Niikura Takako
 

Niikura Takako

 
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NameNiikura Takako
AffiliationSophia University
SectionFaculty of Science and Technology, Department of Information and Communication Sciences
Job titleProfessor
DegreePhD(The University of Tokyo)
J-Global ID201301051278280653

Profile

1989-1991 Researcher Safety Research Institute for Chemical Compounds (Japan) 1991-1992 Research Assistant Tonen K.K. Institute of Basic Science (Japan) 1992-1993 Higher Scientific Officer Institute of Virology and Environmental Microbiology, NERC (UK) 1994-1995 Postdoctoral Fellow Thomas Jefferson University, School of Medicine (USA) 1995-1997 Research Associate Michigan State University, Department of Biochemistry (USA) 1997-2007 Assistant Professor/Instructor KEIO University, School of Medicine (Japan) 2007 - 2009 Research Assistant Professor Georgetown University, Department of Neurology (USA) 2009 - 2012 Assistant Professor Simon Fraser University, Faculty of Health Sciences (Canada) 2012-present Associate Professor Sophia University, Faculty of Science and Technology (Japan)

Research Interests

 
Neurodegenerative disorders ,Humanin ,Aging

Research Areas

 
  • Life sciences / Neuroanatomy and physiology / 
  • Life sciences / Neuroscience - general / 

Papers

 
 
Tsutomu Arakawa   Takako Niikura   Yoshiko Kita   Teruo Akuta   
Current Issues in Molecular Biology   46(1) 621-633   Jan 2024   [Refereed]
In this study, we review the properties of three anionic detergents, sodium dodecyl sulfate (SDS), Sarkosyl, and sodium lauroylglutamate (SLG), as they play a critical role in molecular biology research. SDS is widely used in electrophoresis and c...
 
Christian Nanga Chick   Yusuke Sasaki   Mari Kawaguchi   Eri Tanaka   Takako Niikura   Toyonobu Usuki   
Bioorganic & Medicinal Chemistry   90 117351-117351   Jul 2023   [Refereed]
 
Natsumi Ikegawa   Ayari Kozuka   Nozomi Morita   Minetaka Murakami   Nobuyuki Sasakawa   Takako Niikura   
Biochimica et Biophysica Acta (BBA) - General Subjects   1866(10) 130204-130204   Oct 2022   [Refereed]
 
Takako Niikura   
Biochimica et Biophysica Acta (BBA) - General Subjects   1866(1) 130024-130024   Jan 2022   [Refereed]
 
Tsutomu Arakawa   Masao Tokunaga   Yoshiko Kita   Takako Niikura   Richard W. Baker   Janice M. Reimer   Andres E. Leschziner   
The Protein Journal   40(6) 867-875   Dec 2021   [Refereed]

Misc.

 
 
T. Arakawa   A. Hirano   K. Shiraki   T. Niikura   Y. Kita   
Current Medicinal Chemistry   18(36) 5554-5563   2011   
Humanin (HN), a short amino acid peptide, protects neurons as well as other cells from amyloid β-induced toxicities and other stresses. A number of HN binding proteins have been identified and their involvements in HN-mediated neuroprotection have...
 
Arakawa T   Niikura T   Kita Y   Arisaka F   
Drug Discoveries & Therapeutics   3(5) 208-214   Aug 2009   
 
T. Arakawa   Y. Kita   T. Niikura   
CURRENT MEDICINAL CHEMISTRY   15(21) 2086-2098   Sep 2008   
Alzheimer's disease (AD) is a complex disease, involving multiple factors such as the production of aggregation-prone amyloid (A peptides, the formation of fibrillarly tangles of microtubule-associating proteins, Tau, and the polymorphism of chole...
 
Takako Niikura   
Expert Opinion on Drug Discovery   2(9) 1273-1282   Aug 2007   
 
Yoichiro Abe   Yoshiko Kita   Takako Niikura   
JOURNAL OF PHARMACOLOGICAL SCIENCES   103 177P-177P   2007   

Books and Other Publications

 
 

Presentations

 
 
A Kozuka   T Niikura   
第96回日本薬理学会年会   Dec 2022   
 
N Ikegawa   A Kozuka   N Morita   M Murakami   N Sasakawa   T Niikura   
Society for Neuroscience 51st Annual Meeting 2022   Nov 2022   
 
Ayari Kozuka   Dan Suzuki   Takako Niikura   
第65回日本神経化学会年会   2022   
 
T Niikura   N Morita   A Kozuka   N Ikegawa   N Sasakawa   
第64回⽇本神経化学会⼤会   2021   
 
N Ikegawa   M Murakami   T Niikura   
Society for Neuroscience 49th Annual Meeting 2019   2019   

Research Projects

 
 
アルツハイマー病病態改善ペプチド因子の産生制御と抗老化因子としての役割
日本学術振興会: 科学研究費助成事業 基盤研究(C)
新倉 貴子 
Project Year: Apr 2021 - Mar 2024
 
The role of a cytoprotective peptide factor against Alzheimer's disease pathologies in anti-brain aging
Japan Society for the Promotion of Science: Grants-in-Aid for Scientific Research
NIIKURA Takako 
Project Year: Apr 2018 - Mar 2022
 
Elucidation of pathomechanism of Alzheimer's disease focusing on AQP4 function and lymphatic drainage system in the brain.
Japan Society for the Promotion of Science: Grants-in-Aid for Scientific Research Grant-in-Aid for Challenging Research (Exploratory)
Abe Yoichiro 
Project Year: Jun 2017 - Mar 2019
 
Investigation of an underlying mechanism of progression from accumulation of Abeta to neurofibrillary tangle formation using Alzheimer's model mice
Japan Society for the Promotion of Science: Grants-in-Aid for Scientific Research Grant-in-Aid for Challenging Exploratory Research
ABE Yoichiro NIIKURA Takako 
Project Year: Apr 2013 - Mar 2015
 
Molecular mechanisms of amyloid beta metabolism by a cell survival factor
Japan Society for the Promotion of Science: Grants-in-Aid for Scientific Research Grant-in-Aid for Research Activity Start-up
NIIKURA Takako 
Project Year: 2012 - 2013

Other

 
 
「ヒトの生物科学」のタイトルで「ヒト」をキーワードとした生物学・医学・工学・化学の広範な領域のトピックを最近の知見を含めて解説する講義をコーディネートしている。全学共通科目として多くの受講者が興味を持ちかつより深い理解ができるよう工夫している。
 
 
少人数の学部科目において発表会形式のプレゼンテーションを実施し、受講者がプレゼンテーション資料の作成から発表までの一連の作業を経験することで、その後の卒業研究などに自発的に取り組む重要性を理解できるよう工夫している。