Kondo Jiro

Name	Kondo Jiro
URL	https://jkondo.wixsite.com/sophia-biophysics
Affiliation	Sophia University
Section	Faculty of Science and Technology, Department of Materials and Life Sciences
Job title	Associate Professor
Degree	学士（工学）(立命館大学), 修士（理学）(東京工業大学), 博士（理学）(東京工業大学)
Research funding number	10546576
J-Global ID	200901072722483790

Profile

2001-2004: Tokyo Institute of Technology (Ph.D course)
"Structural studies of repetitive DNA sequences in the human genome"
2004-2010: Universite de Strasbourg (Postdoctoral researcher)
"Structural studies of the ribosomal RNA molecular switches"
2010-Present: Sophia University (Assistant Professor)
"Motion picture crystallography of DNA/RNA molecular switches"(Subject of research)
Structural studies on antibiotic-resistance mechanisms and their application to drug design
DNAを利用する重金属イオン除去膜、導電性ワイヤーの開発研究―構造、物性、応用
分子・励起分子・イオンの電子構造と反応・ダイナミックスの解明
ナンセンス突然変異型遺伝病に対するリードスルー治療薬のStructure-Based Design
「顧みられない熱帯病(NTDs)」治療を目的とした新規アミノグリコシド系抗原虫薬のStructure-Based Design
ナンセンス変異型遺伝性疾患への抗生物質の薬理メカニズムの解明と新規治療薬の開発
「顧みられない熱帯病」をターゲットとした新規フッ素化アミノグリコシド薬剤のStructure-Base Design
DNA-金属ハイブリッドナノワイヤー・ナノケージのStructure-Base Design
孵化酵素-基質複合体の３次元構造の解明
インフルエンザウイルスゲノムRNAの構造学的研究と新規インフルエンザ治療薬の開発
DNA二重鎖中で無限に金属イオンが連続する超分子錯体：精密合成・結晶構造・物性
DNAものづくりプラットフォームによるDNA医薬品の開発
放射光Ｘ線結晶解析とクライオ電子顕微鏡を融合した構造生物模倣科学の開拓
貴金属とDNAを融合させたバイオ・ナノデバイスのStructure-Based Design

Research Interests

X-Ray crystallography ,Drug resistance ,Antibiotics ,生体機能応用デバイス ,物理系薬学

Research Areas

Life sciences / Pharmaceuticals - analytical and physicochemistry /
Life sciences / Biophysics /
Life sciences / Structural biochemistry /

Research History

Jan 2009

Mar 2010

Universite de Strasbourg Postdoctoral fellow

Apr 2006

Dec 2008

Universite Louis Pasteur Postdoctoral fellow

Apr 2004

Apr 2006

Universite Louis Pasteur JSPS research fellow

Education

Apr 2001

Mar 2004

Tokyo Institute of Technology Graduate School, Division of Life Science and Engineering

Apr 2001

Mar 2004

Tokyo Institute of Technology Graduate School, Division of Life Science and Engineering

Apr 1999

Mar 2001

Tokyo Institute of Technology Graduate School, Division of Life Science and Engineering

Apr 1999

Mar 2001

Tokyo Institute of Technology Graduate School, Division of Life Science and Engineering

Apr 1995

Mar 1999

Ritsumeikan University Faculty of Science and Engineering

Awards

12 >

Mar 2022

Sophia University, Attractive Lecture Award 2020

Mar 2020

田中貴金属記念財団, 2019年度「貴金属に関わる研究助成金」奨励賞
Jiro Kondo

Dec 2018

上智大学理工学部, Attractive Lecture Award 2018,生物物理学

Dec 2017

上智大学理工学部, Attractive Lecture Award 2017,基礎生物学

Apr 2015

Ministry of Education, Culture, Sports, Science and Technology, The Commendation for Science and Technology by the Minister of Education, Culture, Sports, Science and Technology, The Young Scientists' Prize
Jiro Kondo

Papers

12 3 4 5 >

Synthesis and properties of fully-modified 4′-selenoRNA, an endonuclease-resistant RNA analog

Masashi Ota Hiromi Takahashi Yuhei Nogi Yuma Kagotani Noriko Saito-Tarashima Jiro Kondo Noriaki Minakawa

Bioorganic & Medicinal Chemistry 76 117093-117093 Dec 2022 [Refereed]

A Novel Ag(I)‐DNA Rod Comprising a One‐Dimensional Array of 11 Silver Ions within a Double Helical Structure

Takahiro Atsugi Akira Ono Miho Tasaka Natsumi Eguchi Shoji Fujiwara Jiro Kondo

Angewandte Chemie International Edition 61 May 2022 [Refereed]

DNA Manufacturing Based on Structural Biomimetics

Jiro Kondo

BIO INDUSTRY 39 2022 [Invited]

RNA立体構造モチーフを活用した核酸医薬品のデザイン

Jiro Kondo

PHARM STAGE 22 2022 [Invited]

The effect of inosine on the spectroscopic properties and crystal structure of a NIR-emitting DNA-stabilized silver nanocluster

Cecilia Cerretani Mikkel Liisberg Vanessa Rück Jiro Kondo Tom Vosch

Nanoscale Advances published online 2022 [Refereed]

The effect of replacing guanosines with inosines in the two stabilizing strands (5’-CACCTAGCGA-3’) of the NIR emissive DNA-Ag16NC was investigated. The spectroscopic behavior of the inosine mutants is position-dependent: when...