林謙介

研究者氏名	林謙介
	ハヤシケンスケ
URL
所属	上智大学
部署	理工学部物質生命理工学科
職名	教授
学位	理学博士(東京大学)
科研費研究者番号	50218567
J-Global ID	200901093609757481

プロフィール

1983-1988　東京大学大学院理学研究科生物学専攻　ニワトリ胚消化管の発生に関する研究 1988-1993　国立精神神経センターI神経研究所　ニワトリ胚骨格筋の発生に関する研究 1993-1998　群馬大学医学部　神経細胞のアクチン結合タンパクに関する研究 1998-2004　群馬大学生体調節研究所　神経細胞の細胞極性と細胞移動に関する研究 2004-現在　上智大学理工学部　神経細胞の微小管形成に関する研究

研究分野

ライフサイエンス / 細胞生物学 /
ライフサイエンス / 発生生物学 /

論文

<5 678 9 >

Modulatory role of drebrin on the cytoskeleton within dendritic spines in the rat cerebral cortex

K Hayashi R Ishikawa LH Ye XL He K Takata K Kohama T Shirao

JOURNAL OF NEUROSCIENCE 16(22) 7161-7170 1996年11月

Morphological changes in the dendritic spines have been postulated to participate in the expression of synaptic plasticity. The cytoskeleton is likely to play a key role in regulating spine structure. Here we examine the molecular mechanisms respo...

K252a, a potent inhibitor of protein kinases, inhibits the migration of cerebellar granule cells in vitro

S Kobayashi K Isa K Hayashi HK Inoue K Uyemura T Shirao

DEVELOPMENTAL BRAIN RESEARCH 90(1-2) 122-128 1995年12月

In order to elucidate the cellular mechanisms of migrating neurons, we developed an assay system in vitro, using an aggregation culture of developing granule cells from the rat cerebellum. This assay system allowed us to eliminate the effects of v...

MYOGENIC CELL-MIGRATION FROM SOMITES IS INDUCED BY TISSUE CONTACT WITH MEDIAL REGION OF THE PRESUMPTIVE LIMB MESODERM IN CHICK-EMBRYOS

K HAYASHI E OZAWA

DEVELOPMENT 121(3) 661-669 1995年3月

It is known that myogenic cells in limb buds are derived from somites. In order to examine the potential of the limb primordium (presumptive limb somatopleure) to induce myogenic cell migration, we transplanted chick presumptive limb somatopleure ...

MORPHOLOGICAL-CHANGES OF CEREBELLAR GRANULE CELLS ASSOCIATED WITH INHIBITION OF MIGRATION INDUCED BY K252A IN-VITRO

S TANAKA K HAYASHI K ISA T SHIRAO

JOURNAL OF NEUROCHEMISTRY 65 S91-S91 1995年

DREBRIN, A DEVELOPMENT-ASSOCIATED BRAIN PROTEIN FROM RAT EMBRYO, CAUSES THE DISSOCIATION OF TROPOMYOSIN FROM ACTIN-FILAMENTS

R ISHIKAWA K HAYASHI T SHIRAO YH XUE T TAKAGI Y SASAKI K KOHAMA

JOURNAL OF BIOLOGICAL CHEMISTRY 269(47) 29928-29933 1994年11月

Drebrin is a development-associated neuroprotein whose cDNA into fibroblasts causes the formation of dendrite-like structures (Shirao, T., Kojima, N., and Obata, K. (1992) Neuroreport 3, 109-112). To explore molecular functions of drebrin during b...