JOURNAL OF PLANT BIOLOGY 52(6) 616-624 2009年12月 [査読有り]
Comparative analysis of nucleotide sequences of the genomic region located around 100 map unit of chromosome 1 using two accessions, Columbia (Col) and Landsberg erecta (Ler), of Arabidopsis thaliana was performed. High divergence was detected bet...
The polyketide DIF-1 induces Dictyostelium amoebae to fonn stalk cells in culture. To better define its role in normal development, we examined the phenotype of a mutant blocking the first step of DIF-1 synthesis, which lacks both DIF-1 and its bi...
Michael B. Austin   Tamao Saito   Marianne E. Bowman   Stephen Haydock   Atsushi Kato   Bradley S. Moore   Robert R. Kay   Joseph P. Noel   
NATURE CHEMICAL BIOLOGY 2(9) 494-502 2006年9月 [査読有り]
Differentiation-inducing factors (DIFs) are well known to modulate formation of distinct communal cell types from identical Dictyostelium discoideum amoebas, but DIF biosynthesis remains obscure. We report complimentary in vivo and in vitro experi...
T Saito   GW Taylor   JC Yang   D Neuhaus   D Stetsenko   A Kato   RR Kay   
BIOCHIMICA ET BIOPHYSICA ACTA-GENERAL SUBJECTS 1760(5) 754-761 2006年5月 [査読有り]
Developing Dictyostelitium discoideum amoebae form a stalked fruiting body in which individual cells differentiate into either stalk cells or spores. The major known inducer of stalk cell differentiation is the chlorinated polyketide DIF-1 (1-(3,5...
The social amoebae are exceptional in their ability to alternate between unicellular and multicellular forms. Here we describe the genome of the best-studied member of this group, Dictyostelium discoideum. The gene-dense chromosomes of this organi...