Jiro Kondo   Yoshinari Tada   Takenori Dairaku   Yoshikazu Hattori   Hisao Saneyoshi   Akira Ono   Yoshiyuki Tanaka   
NATURE CHEMISTRY 9(10) 956-960 2017年10月 [査読有り]
The double-helix structure of DNA, in which complementary strands reversibly hybridize to each other, not only explains how genetic information is stored and replicated, but also has proved very attractive for the development of nanomaterials. The...
Takenori Dairaku   Kyoko Furuita   Hajime Sato   Jakub Sebera   Katsuyuki Nakashima   Jiro Kondo   Daichi Yamanaka   Yoshinori Kondo   Itaru Okamoto   Akira Ono   Vladimir Sychrovsky   Chojiro Kojima   Yoshiyuki Tanaka   
CHEMISTRY-A EUROPEAN JOURNAL 22(37) 13028-13031 2016年9月 [査読有り]
The structure of an Ag-I-mediated cytosine-cytosine base pair, C-Ag-I-C, was determined with NMR spectroscopy in solution. The observation of 1-bond N-15-Ag-109 J-coupling ((1)J(N-15, Ag-109): 83 and 84 Hz) recorded within the C-Ag-I-C base pair e...
CHEMICAL COMMUNICATIONS 52(11) 2354-2357 2016年 [査読有り]
It has been confirmed by our previous studies that a 2',4'-BNA(NC)[N-Me]-modified antisense gapmer displays high affinity and selectivity to the target RNA strand, promising mRNA inhibitory activity and excellent nuclease resistance. Herein, we ha...