Detecting natural selection would provide valuable insight into the molecular mechanisms of pathogenesis and advanced knowledge about the history of human adaptations to local environments. This study tried to detect natural selection in pigmentat...
Sumiko Anno   Kazuhiko Ohshima   Takashi Abe   
Expert Review of Molecular Diagnostics 10(8) 987-991 2010年11月 [査読有り]
Genetic and environmental factors are both part of an elaborate feedback mechanism whereby the human adaptive form reacts to environmental stimuli via internal adjustments. Human survival may ultimately depend on understanding two important compon...
Sumiko Anno   Takashi Abe   Takushi Yamamoto   
International Journal of Biological Sciences 4(2) 81-86 2008年 [査読有り]
This study aimed to identify single nucleotide polymorphism (SNP) alleles at multiple loci associated with racial differences in skin color using SNP genotyping. A total of 122 Caucasians in Toledo, Ohio and 100 Mongoloids in Japan were genotyped ...