Hashimoto Takeshi

Phenylboronic acid azoprobe (B-Azo-Cb) for saccharide recognition was synthesized. B-Azo-Cb/polyamidoamine (PAMAM) complex was synthesized by the condensation reaction of terminal carboxylic group of B-Azo-Cb and surface amine of PAMAM dendrimer. Thin porous cellulose acetate membrane embedded with B-Azo-Cb/PAMAM dendrimer complex was prepared from cellulose acetate, formamide, acetone, and B-Azo-Cb/PAMAM dendrimer complex by casting on the glass plate at various temperatures. The saccharide transportability was evaluated by measuring the amount of saccharide in receiving solution. The amount of saccharide transport of porous cellulose acetate membrane embedded with B-Azo-Cb/PAMAM dendrimer complex was higher at low temperature-treated membrane, and low pH of receiving solution. In contrast, the saccharide transportabilities through non-treated cellulose acetate membrane were the same at any pH of receiving solution.

For ion and molecule recognition based on supramolecular chemistry, organic receptors are often used as molecular probes. In addition, the metal complex formation with various organic ligands has played an important role in hostguest chemistry. In this paper, "molecular recognition based on metal complexes" using so-called Werner-type metal complexes is reviewed. In these systems, the metal complexes (compounds having metal-ligand coordinations) are acting as a host (chemosensor or molecule probe), and they selectively recognize various guest molecules with electro and/or photo-sensitive signal transductions. As a topic of "molecular recognition based on metal complexes", we have focused on the recent research progress in 1) ion (cation, anion) recognition, 2) biomolecule recognition, and 3) recognition by polymer complexes, from the viewpoint of authors' interest.